William Mobley, the newly appointed chairman of the Department of Neurosciences at UCSD published a paper today in Science Translational Medicine showing that boosting levels of the neurotransmitter, neuropinephrine, in a particular part of the brain, the locus coeruleus, reversed some of the cognitive deficits in a mouse model of Down Syndrome.  This work adds to the fascinating data in recent years showing that neurodevelopmental disorders such as Down, Rett Syndrome, Fragile X, and others may be treatable.

UCSD Press Release
The Scientist – A Fix For Down Syndrome Brains?